Understanding tolerance following immune reconstitution in MS

Dr Jennifer Massey

St Vincent's Hospital, NSW

| Better treatments | Immunology | Fellowship | 2020 | Investigator Led Research |


Dr Jennifer Massey’s research focuses on AHSCT (Autologous Haematopoietic Stem Cell Transplantation) and other therapies that deplete parts of the immune system. She is particularly interested in how the immune system regrows after these therapies. She analyses blood and plasma samples of people with MS prior to, and at specific time points following treatment with AHSCT.

Dr Massey aims to shed light on the underlying cause of MS and how, once depleted, the immune systems regrows or reboots to restore a functional immune system. Specifically, she aims to identify changes in the balance of white blood cells that prevent inflammation and white blood cells that cause inflammation. This will give us key insights into the immune system post-AHSCT, and may help in enhancing understanding of how AHSCT works for MS.

Updated 22 January 2020

Updated: 21 January, 2020

Stages of the research process

Fundamental laboratory

Laboratory research that investigates scientific theories behind the possible causes, disease progression, ways to diagnose and better treat MS.

Lab to clinic timeline: 10+ years

Research that builds on fundamental scientific research to develop new therapies, medical procedures or diagnostics and advances it closer to the clinic.

Lab to clinic timeline: 5+ years
Clinical Studies
and Clinical Trials

Clinical research is the culmination of fundamental and translational research turning those research discoveries into treatments and interventions for people with MS.

Lab to clinic timeline: 1-5 years



Grant Awarded

  • Postdoctoral Fellowship

Total Funding

  • $180,000


  • 3 years over 2020 - 2022

Funding Partner

  • MS Angels
Contact Us

We're not around right now. But you can send us an email and we'll get back to you, asap.

Start typing and press Enter to search