Understanding tolerance following immune reconstitution in MS
Dr Jennifer Massey
St Vincent's Hospital, NSW
Summary
Dr Jennifer Massey’s research focuses on AHSCT (Autologous Haematopoietic Stem Cell Transplantation) and other therapies that deplete parts of the immune system. She is particularly interested in how the immune system regrows after these therapies. She analyses blood and plasma samples of people with MS prior to, and at specific time points following treatment with AHSCT.
Dr Massey aims to shed light on the underlying cause of MS and how, once depleted, the immune systems regrows or reboots to restore a functional immune system. Specifically, she aims to identify changes in the balance of white blood cells that prevent inflammation and white blood cells that cause inflammation. This will give us key insights into the immune system post-AHSCT, and may help in enhancing understanding of how AHSCT works for MS.
Updated 22 January 2020
Updated: 21 January, 2020
Stages of the research process
Fundamental laboratory
Research
Research
Laboratory research that investigates scientific theories behind the possible causes, disease progression, ways to diagnose and better treat MS.
Lab to clinic timeline: 10+ years
Translational
Research
Research
Research that builds on fundamental scientific research to develop new therapies, medical procedures or diagnostics and advances it closer to the clinic.
Lab to clinic timeline: 5+ years
Clinical Studies
and Clinical Trials
and Clinical Trials
Clinical research is the culmination of fundamental and translational research turning those research discoveries into treatments and interventions for people with MS.
Lab to clinic timeline: 1-5 years
Grant Awarded
- Postdoctoral Fellowship
Total Funding
-
$180,000
Duration
-
3 years – starting 2020
Funding Partner
- MS Angels
