MS is one of the most common neurological causes of disability among young adults. Living further away from the equator is associated with less exposure to UV from the sun and less vitamin D production, and is also linked to a higher rates of MS. These and other findings support a significant role for vitamin D in the development of MS. Dr Wei Yeh aims to determine the effects that vitamin D has on immune cells in people with MS, and how this is different to people without MS. This will shed further light on the role of vitamin D in MS risk and will help determine ways to prevent the development of MS.
Additionally, Dr Yeh will also investigate factors that might influence the risk of relapses during pregnancy. Previous studies have shown a drop in the risk of relapse during pregnancy. Dr Yeh will use data from MSBase, a large international registry of people with MS, to find factors that predict relapse in pregnancy. These findings will help guide what to do in the clinic to minimise the chances of a relapse during pregnancy.
Updated: 21 January, 2020
Laboratory research that investigates scientific theories behind the possible causes, disease progression, ways to diagnose and better treat MS.
Research that builds on fundamental scientific research to develop new therapies, medical procedures or diagnostics and advances it closer to the clinic.
Clinical research is the culmination of fundamental and translational research turning those research discoveries into treatments and interventions for people with MS.