People with MS are more likely to experience depression, causing significant burden to the individual and the healthcare system. New therapies for depression that are effective, inexpensive and tolerable are urgently needed. Healthy diets that are rich in fruits and vegetables have been shown in several recent studies to improve depressive symptoms. One suggested reason for this effect is due to the high concentration of polyphenols, (micronutrients found in fruits and vegetables), which have a wide range of beneficial properties believed to be relevant to improving depression. Also, people who consume higher levels of polyphenols in their diet have been shown to have a decreased risk of depression. While the evidence is promising, the role of polyphenols in improving depression in people with MS has not yet been studied.
This will be the first research program internationally, using gold standard study designs, to thoroughly investigate the role of polyphenols in managing depression in MS. If shown to be effective, this research will provide strong evidence for the role of a tolerable, low-cost, and widely available strategy to help improve depression in people with MS.
Updated 22 January 2020
Updated: 21 January, 2020
Laboratory research that investigates scientific theories behind the possible causes, disease progression, ways to diagnose and better treat MS.
Research that builds on fundamental scientific research to develop new therapies, medical procedures or diagnostics and advances it closer to the clinic.
Clinical research is the culmination of fundamental and translational research turning those research discoveries into treatments and interventions for people with MS.